Hoechst 34580 (tetrahydrochloride)
| 中文名称 | Hoechst 34580 (tetrahydrochloride) |
|---|---|
| 中文同义词 | 赫斯特34580 四盐酸盐;Hoechst 34580 tetrahydrochloride试剂;Hoechst 34580 tetrahydrochloride试剂;化合物 Hoechst 34580 tetrahydrochloride;N,N-二甲基-4-(6-(4-甲基哌嗪-1-基)-1H,3'H-[2,5'-联苯并[d]咪唑]-2'-基)苯胺盐酸盐 |
| 英文名称 | Hoechst 34580 (tetrahydrochloride) |
| 英文同义词 | Hoechst 34580 (tetrahydrochloride) |
| CAS号 | 2310135-08-9 |
| 分子式 | C??H??Cl?N? |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
Hoechst 34580 (tetrahydrochloride) 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 浅黄至卡其色 |
Hoechst 34580 tetrahydrochloride是一种细胞渗透性的荧光染料，用于DNA和核染色。
Amyloid-β
Hoechst 34580 prefers to locate near hydrophobic regions with binding affinity with the inhibition constant IC 50 of 0.86±0.05 μM for Hoechst 34580. Hoechst 34580 is a good candidate for treating the Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. And the half-maximal concentration (IC 50 ) is examined. The IC 50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-15560B | Hoechst 34580 (tetrahydrochloride) Hoechst 34580 tetrahydrochloride | 2310135-08-9 | 5mg | 600元 |
| 2025/12/22 | HY-15560B | Hoechst 34580 (tetrahydrochloride) Hoechst 34580 tetrahydrochloride | 2310135-08-9 | 10mg | 900元 |