| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:Carmoxirole hydrochloride CAS:115092-85-8 Purity:98% Package:25MG; 100MG; 500MG;1G; 5G; 10G
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1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) manufacturers
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| | 1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) Basic information |
| Product Name: | 1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) | | Synonyms: | EMD 45609 hydrochloride;inhibit,Carmoxirole,Dopamine Receptor,Carmoxirole hydrochloride,Inhibitor,EMD-45609,EMD 45609,EMD45609;Carmoxirole hydrochloride, 10 mM in DMSO;Carmoxirole HCl | | CAS: | 115092-85-8 | | MF: | C24H26N2O2.ClH | | MW: | 410.94 | | EINECS: | | | Product Categories: | | | Mol File: | 115092-85-8.mol | ![1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) Structure](CAS/20180601/GIF/115092-85-8.gif) |
| | 1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) Chemical Properties |
| Melting point | 298-299° | | storage temp. | Store at -20°C | | solubility | Soluble to 100 mM in DMSO | | form | Powder | | color | Yellow to brown |
| | 1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) Usage And Synthesis |
| Uses | Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo[1]. | | Definition | ChEBI: Carmoxirole hydrochloride is a hydrochloride salt obtained by reaction of carmoxirole with one equivalent of hydrochloric acid. Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo. It has a role as a dopamine agonist, an antihypertensive agent and a platelet aggregation inhibitor. It contains a carmoxirole(1+). | | IC 50 | D2 Receptor | | References | [1] Haase AF, et al. Neurochemical profile of EMD 45609 (carmoxirole), a dopamine DA2-receptor agonist. Naunyn Schmiedebergs Arch Pharmacol. 1991 Jun;343(6):588-94. DOI:10.1007/BF00184289 |
| | 1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, hydrochloride (1:1) Preparation Products And Raw materials |
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