- Catharanthine Tartrate
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- $3.00 / 25KG
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2025-10-13
- CAS:4168-17-6
- Min. Order: 0.1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | CATHARANTHINE TARTRATE Basic information |
| Product Name: | CATHARANTHINE TARTRATE | | Synonyms: | CATHARANTHINE TARTRATE;7-ETHYL-9,10,12,13-TETRAHYDRO-6,9-METHANO-5H-PYRIDO[1',2':1,2]AZEPINO[4,5-B]INDOLE-6(6AH)-CARBOXYLIC ACID METHYL ESTER TARTRATE;(2alpha,5beta,6alpha,18beta)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester (2R,3R)-2,3-dihydroxybutanedioate;Catharanthine hemitartrate;(2α,5β,6α,18β)-3,4-Didehydro-ibogaMine-18-carboxylic Acid Methyl Ester Tartrate;Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate;CATHARANTHINE TARTRATE USP/EP/BP;Levofolene | | CAS: | 4168-17-6 | | MF: | C25H30N2O8 | | MW: | 486.51 | | EINECS: | | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Anti-cancer & immunity;Inhibitors;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | Mol File |  |
| | CATHARANTHINE TARTRATE Chemical Properties |
| Melting point | 145-1470C | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated) | | form | White to off-white crystalline powder. | | color | White to Pale Beige | | InChIKey | JYBKPXVXYJDIFX-GYMDHWDQSA-N | | SMILES | [C@]12(C(OC)=O)[C@]3(C(=C[C@]([H])(CN3CCC3C4=C(C=CC=C4)NC1=3)C2)CC)[H].C(O)(C(O)=O)C(O)C(O)=O |
| | CATHARANTHINE TARTRATE Usage And Synthesis |
| Chemical Properties | Off-White to Pale Beige Solid | | Uses | Precursor of Vinblastine-type alkaloids. | | in vivo | Catharanthine ((+)-3,4-Didehydrocoronaridine; 0.5-20 mg/kg; IV; single dose) Tartrate evokes dose-dependent reductions in both BP and HR[1].
Catharanthine (40 mg/kg; ip; single dose) Tartrate with acute administration induces similar antidepressant-like activity in male and female mice at 1 h and 24 h[1].
Catharanthine (20 mg/kg; ip; for 14 consecutive days) Tartrate increases swimming time and decreases immobility time at D7 or D14 in mice[1].
| Animal Model: | 13-week-old male SpragueDawley rats (300-350 g)[1] | | Dosage: | 0.5-20 mg/kg | | Administration: | IV; single dose | | Result: | Evoked rapid, transient reductions in BP and HR (lasting ,2 minutes) at low doses (0.5–5 mg/kg), whereas at higher doses (10 and 20 mg/kg), the BP and HR reductions were sustained.
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| | IC 50 | L-type calcium channel |
| | CATHARANTHINE TARTRATE Preparation Products And Raw materials |
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