| Company Name: |
Nanjing Chemlin Chemical Co., Ltd
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| Tel: |
025-83697070 13913916777 |
| Email: |
info@chemlin.com.cn |
| Products Intro: |
Product Name:QC6352; 3-[[[(1R)-1,2,3,4-Tetrahydro-6-(methylphenylamino)-1-naphthalenyl]methyl]amino]-4-pyridinecarboxylic acid CAS:1851373-36-8
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| Company Name: |
ShangHai Caerulum Pharma Discovery Co., Ltd.
|
| Tel: |
18149758185 18149758185 |
| Email: |
sales-cpd@caerulumpharma.com |
| Products Intro: |
Product Name:QC6352 CAS:1851373-36-8 Purity:98% Package:10mg;100mg;1g;10g;100g;1kg
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QC6352 manufacturers
- QC6352
-
- $1980.00 / 50mg
-
2026-04-21
- CAS:1851373-36-8
- Min. Order:
- Purity:
- Supply Ability: 10g
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| Product Name: | QC6352 | | Synonyms: | CPD1548;QC6352;4-Pyridinecarboxylic acid, 3-[[[(1R)-1,2,3,4-tetrahydro-6-(methylphenylamino)-1-naphthalenyl]methyl]amino]-;QC-6352,QC6352 | | CAS: | 1851373-36-8 | | MF: | C24H25N3O2 | | MW: | 387.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1851373-36-8.mol |  |
| | QC6352 Chemical Properties |
| Boiling point | 681.6±55.0 °C(Predicted) | | density | 1.243±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 25 mg/mL (64.52 mM) | | form | Solid | | pka | 1.55±0.36(Predicted) | | color | Light yellow to yellow |
| | QC6352 Usage And Synthesis |
| Uses | 3-[[[(1R)-1,2,3,4-Tetrahydro-6-(methylphenylamino)-1-naphthalenyl]methyl]amino]-4-Pyridinecarboxylic Acid is also known as a KDM4 inhibitor exhibiting antiproliferative effects in cancer models. | | in vivo | QC6352 strongly affects tumor growth and final tumor weight of both BCSC1 and BCSC2 xenografts. Treatment with QC6352 is well tolerated and does not affect body weight of the mice. Results demonstrate that treatment with the KDM4 inhibitor QC6352 blocks BCSC xenograft tumor growth[2]. | | IC 50 | KDM4; KDM5B: 750 nM (IC50); KDM4A: 104 nM (IC50); KDM4B: 56 nM (IC50); KDM4C: 35 nM (IC50); KDM4D: 104 nM (IC50) |
| | QC6352 Preparation Products And Raw materials |
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