11-Azido-undecanoic acid manufacturers
- N3-C10-COOH
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- $0.00 / 250mg
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2025-06-07
- CAS:118162-45-1
- Min. Order: 250mg
- Purity: >95.00%
- Supply Ability: 250mg
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| | 11-Azido-undecanoic acid Basic information |
| Product Name: | 11-Azido-undecanoic acid | | Synonyms: | 11-Azido-undecanoic acid;N3-C10-COOH;11-Azidoundecanoic acid - [A9114];11-Azidoundecanoic acid , 11-Azidoundecanoic acid | | CAS: | 118162-45-1 | | MF: | C11H21N3O2 | | MW: | 227.30334 | | EINECS: | | | Product Categories: | | | Mol File: | 118162-45-1.mol |  |
| | 11-Azido-undecanoic acid Chemical Properties |
| storage temp. | 4°C, protect from light | | form | Solid | | color | White to off-white |
| | 11-Azido-undecanoic acid Usage And Synthesis |
| Description | 11-Azidoundecanoic acid is a linker containing an azide group and a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | 11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling[1][2]. 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | References | [1] Fernández-Suárez M, et al. Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol. 2007 Dec;25(12):1483-7. DOI:10.1038/nbt1355
[2] Heal WP, et al. N-Myristoyl transferase-mediated protein labelling in vivo. Org Biomol Chem. 2008 Jul 7;6(13):2308-15. DOI:10.1039/b803258k |
| | 11-Azido-undecanoic acid Preparation Products And Raw materials |
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