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| | Fluo-2 AM Basic information |
| Product Name: | Fluo-2 AM | | Synonyms: | Glycine, N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[4-[6-[(acetyloxy)methoxy]-3-oxo-3H-xanthen-9-yl]-2-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-, (acetyloxy)methyl ester | | CAS: | 1070771-36-6 | | MF: | C51H52N2O23 | | MW: | 1060.96 | | EINECS: | | | Product Categories: | | | Mol File: | 1070771-36-6.mol |  |
| | Fluo-2 AM Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: Soluble | | form | A solid |
| | Fluo-2 AM Usage And Synthesis |
| Uses | Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration[1]. | | Biological Activity | Fluo-2 AM is a cell-permeable fluorescent calcium indicator.1,2 It has been used to measure the activity of the neuropeptide Y4 receptor, as well as to detect intracellular calcium in tetrandine-stimulated primary rabbit corpus cavernosum smooth muscle cells. It binds to calcium (Kd = 290 nM) and displays excitation/emission maxima of 490/515 nm, respectively. Fluo-2 AM is also available in a cell-impermeable form . | | References | [1] Sliwoski, G., Schubert, M., Stichel, J., et al.Discovery of small-molecule modulators of the human Y4 receptorPLoS One11(6)e0157146(2016)
[2] Liu, J.-H., Chen, J., Wang, T., et al.Effects of tetrandrine on cytosolic free calcium concentration in corpus cavernosum smooth muscle cells of rabbitsAsian J. Androl.8(4)405-409(2006) |
| | Fluo-2 AM Preparation Products And Raw materials |
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