NEUROPEPTIDE VF (124-131) (HUMAN)
| 中文名称 | NEUROPEPTIDE VF (124-131) (HUMAN) |
|---|---|
| 中文同义词 | 人GNIH 肽同源物;受体激动剂多肽NEUROPEPTIDENPVF-AMIDE;RFRP 3(人类)三氟乙酸盐;化合物 RFRP-3(HUMAN);NPVF 多克隆抗体-E-AB-17956;NPVF 多克隆抗体-E-AB-19861 |
| 英文名称 | H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2 |
| 英文同义词 | (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide;NEUROPEPTIDE NPVF FRAGMENT AMIDE [HOMO SAPIENS];NEUROPEPTIDE VF (124-131) (HUMAN);NPVF;V-8-F-NH2;H2N-VPNLPQRF-AMIDE;Neuropeptide VF (124-131) (huMan) V-8-F-NH2, NPVF;V-8-F-NH2, NPVF |
| CAS号 | 311309-27-0 |
| 分子式 | C45H72N14O10 |
| 分子量 | 969.14 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 311309-27-0.mol |
| 结构式 |  |
NEUROPEPTIDE VF (124-131) (HUMAN) 性质
| 密度 | 1.45±0.1 g/cm3(Predicted) |
|---|---|
| 储存条件 | -15°C |
| 形态 | 粉末 |
| 酸度系数(pKa) | 13.23±0.20(Predicted) |
| 颜色 | 白色至类白色 |
| 水溶解性 | Soluble to 2 mg/ml in 20% acetonitrile / Water |
| InChIKey | JFZCLMZUABKABL-GVCDGELBSA-N |
RFRP-3 efficiently inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM. Scatchard-plot analysis shows that 125 I-labelled hRFRP-3 has a single class of high-affinity binding sites for the membrane fractions of CHO cells expressing rat OT7T022, the K d value and the B max values are 0.19 nM and 1.3 pM, respectively.RFRP-3 specifically stimulate cells transfected with a new orphan 7TMR, OT7T022, it binds to OT7T022 as a specific ligand with high affinity (K d = 0.19 nM).RFRP-3 (10 -8 to 10 -14 M) has no effect on LH and FSH levels alone, but when it combines with GnRH, LH and FSH secretion is significantly reduced by the combination.
安全信息
| WGK Germany | 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-P1250 | NEUROPEPTIDE VF (124-131) (HUMAN) RFRP-3(human) | 311309-27-0 | 1 mg | 560元 |
| 2026/06/05 | HY-P1250 | NEUROPEPTIDE VF (124-131) (HUMAN) RFRP-3(human) | 311309-27-0 | 5 mg | 1400元 |