4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide

4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Suppliers list

Company Name:	Arizest(Shanghai)Pharmatech Co., Ltd
Tel:	+86-021-60753300
Email:	3652837972@qq.com
Products Intro:	Product Name:4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide CAS:1855006-12-0 Purity:90+ Package:10mg;50mg;100mg Remarks:Reference standard

Company Name:	Sinco Pharmachem (ShenZhen) R&D Co., Ltd.
Tel:	+undefined18603013401
Email:	jack.lin@sincopharmachem.com
Products Intro:	Product Name:Regorafenib EP Impurity C CAS:1855006-12-0 Purity:98% HPLC Package:10mg;25mg;50mg;100mg Remarks:COA, 1H NMR, MS, and HPLC purity data provided with shipment.

Company Name:	NANJING YINGWEN BIOTECHNOLOGY CO LTD
Tel:	+8613382787392
Email:	sales@aeechem.com
Products Intro:	CAS:1855006-12-0 Purity:98%

Company Name:	QUALITY CONTROL SOLUTIONS LTD.
Tel:	+86-0755-66853366 +8613670046396
Email:	export03@qcsrm.com
Products Intro:	Product Name:Regorafenib Impurity B CAS:1855006-12-0 Purity:0.95 Package:10mg; 25mg;50mg;100mg Remarks:Brand: QCS; Can provide COA, hydrogen spectrum, mass spectrometry, liquid phase; Level: Pharmaceutical Impurity Standard

Company Name:	Quality Control Solutions Ltd.
Tel:	0755-66853366 13670046396
Email:	orders@qcsrm.com
Products Intro:	Product Name:Regorafenib Impurity B CAS:1855006-12-0 Purity:95% HPLC Package:10mg;25mg;50mg;100mg

4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Basic information

Product Name:	4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide
Synonyms:	4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide;2-Pyridinecarboxamide, 4-[3-fluoro-4-[[2-[(methylamino)carbonyl]-4-pyridinyl]amino]phenoxy]-N-methyl-;Regorafenib Dipyrimidine;4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide formate;Regorafenib Impurities69;Azilsartan medoxomil impurity263;Regorafenib Impurities04;Regorafenib Impurities11
CAS:	1855006-12-0
MF:	C20H18FN5O3
MW:	395.39
EINECS:
Product Categories:
Mol File:	1855006-12-0.mol

4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Chemical Properties

Boiling point	631.8±55.0 °C(Predicted)
density	1.329±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	13.92±0.46(Predicted)
InChIKey	USLJNRHZMUHXEP-UHFFFAOYSA-N
SMILES	Fc1c(ccc(c1)Oc3cc(ncc3)C(=O)NC)Nc2cc(ncc2)C(=O)NC

Safety Information

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

MSDS Information

4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Usage And Synthesis

Uses	Regorafenib Dipyrimidine is an impurity of Regorafenib(R143000); which inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.

4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide Preparation Products And Raw materials

Tag:4-[2-fluoro-4-[2-(methylcarbamoyl)pyridin-4-yl]oxyanilino]-N-methylpyridine-2-carboxamide(1855006-12-0) Related Product Information

2-Pyridinecarboxamide, 4-[2-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl- N-Desmethyl Regorafenib N-Oxide (M5 Metabolite) Regorafenib Impurity 13 Regorafenib Impurity 9 Regorafenib Impurity 10 N-Desmethyl Regorafenib 4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE 4-(4-(3-(4-chloro-3-(trifluoroMethyl)phenyl)ureido)-3-fluorophenoxy)-2-(MethylcarbaMoyl)pyridine 1-oxide Regorafenib Impurity 6 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]phenoxy]-N-methyl- Regorafenib Impurity 17 4-(4-amino-3-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)phenoxy)-N-methylpicolinamide INDEX NAME NOT YET ASSIGNED Regorafenib Impurity 16

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