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| | Nicotine ditartrate Basic information |
| Product Name: | Nicotine ditartrate | | Synonyms: | (-)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt;(-)-Nicotine/L-Tartaric acid,(1:2);(S)-Nicotine/(2R,3R)-Tartaric acid,(1:2);3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate;(-)-Nicotine dirartate;(S)-(-)-1-Methyl-2-(3-pyridyl)pyrrolidine(+)-ditartratesalt;Nicotine Bitartrate anhydrous;(-)-Nicotine ditatrate | | CAS: | 65-31-6 | | MF: | C18H26N2O12 | | MW: | 462.41 | | EINECS: | 200-607-2 | | Product Categories: | EXLAX | | Mol File: | 65-31-6.mol |  |
| | Nicotine ditartrate Chemical Properties |
| Melting point | 90° | | alpha | D20 +26° (c = 10) | | storage temp. | Desiccate at RT | | solubility | H2O: 50 mg/mL | | form | powder | | color | white to off-white | | Optical Rotation | [α]/D +20 to +26°, c = 1.0 in water | | InChI | 1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1 | | InChIKey | RFEJUZJILGIRHQ-UHFFFAOYSA-N | | SMILES | N1(C(CCC1)c2cnccc2)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O[C@H]([C@@H](O)C(=O)O)C(=O)O | | CAS DataBase Reference | 65-31-6(CAS DataBase Reference) | | EPA Substance Registry System | Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (65-31-6) |
| Hazard Codes | T+,N | | Risk Statements | 26/27/28-51/53 | | Safety Statements | 13-28-45-61 | | RIDADR | UN 1659 | | WGK Germany | 2 | | RTECS | QT0350000 | | HazardClass | 6.1 | | PackingGroup | II | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Inhalation
Acute Tox. 3 Oral
Aquatic Chronic 2
Eye Irrit. 2
Repr. 2 | | Hazardous Substances Data | 65-31-6(Hazardous Substances Data) |
| | Nicotine ditartrate Usage And Synthesis |
| Uses | nicotinyl acetylchloline receptor agonist, ectoparasiticide | | Uses | cathartic, laxative | | General Description | Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions. | | Biological Activity | Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo . | | Biochem/physiol Actions | Product does not compete with ATP. | | Safety Profile | Poison by ingestion,
intravenous, intraperitoneal, and
subcutaneous routes. An experimental
teratogen. Experimental reproductive
effects. When heated to decomposition it
emits toxic fumes of NOx and CO. See also
NICOTINE. | | storage | Desiccate at RT |
| | Nicotine ditartrate Preparation Products And Raw materials |
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