FETMPYP manufacturers
- Fe-TMPyP
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- $127.00 / 10mg
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2026-03-13
- CAS:133314-07-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | FETMPYP Basic information |
| Product Name: | FETMPYP | | Synonyms: | FETMPYP;FETMPYP PENTACHLORIDE;FE(III)TETRAKIS(1-METHYL-4-PYRIDYL)PORPHYRIN PENTACHLORIDE;FEIIITMPYP(CL);5,10,15,20-TETRAKIS(N-METHYL-4'-PYRIDYL)PORPHINATO IRON (III) CHLORIDE;Fe(III) meso-Tetra (N-Methyl-4-Pyridyl) porphine pentachloride;Iron(III) meso -tetra(N-methyl-4-pyridyl)porphine pentachloride;5,10,15,20-tetra (1-methyl-4-pyridyl) porphyrin ferric chloride | | CAS: | 133314-07-5 | | MF: | C45H62N8 | | MW: | 715.02738 | | EINECS: | | | Product Categories: | | | Mol File: | 133314-07-5.mol |  |
| | FETMPYP Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 0.1 M Tris -HCl, 1 mM EDTA, pH 9.0: >12 mg/ml; PBS pH 7.2: >10.1 mg/ml | | form | A crystalline solid | | color | Brown to black | | Water Solubility | water: 50mg/mL |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | FETMPYP Usage And Synthesis |
| Description | FeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.2 x 106 M−1s−1 with a turnover number of 360 ± 170 s−1. The predominant product (>90%) of this reaction is nitrate, with a minor amount of nitrite also formed (~6%), at pH 7.4. | | Uses | FeTMPyP is an orally active peroxynitrite (ONOO ) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits[1][2]. | | References | [1] Zhang S, et al. Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging. Oxid Med Cell Longev. 2020 Jan 25;2020:4252047. DOI:10.1155/2020/4252047 [2] Komirishetty P, et al. FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats. Free Radic Res. 2021 Oct;55(9-10):1005-1017. DOI:10.1080/10715762.2021.2010731 |
| | FETMPYP Preparation Products And Raw materials |
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