FETMPYP

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FETMPYP Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
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Company Name: Shanghai Aladdin Bio-Chem Technology Co.,LTD  
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FETMPYP manufacturers

  • Fe-TMPyP
  • Fe-TMPyP pictures
  • $127.00
  • 2026-07-15
  • CAS:133314-07-5
  • Purity:
  • Supply Ability: 10g
FETMPYP Basic information
Product Name:FETMPYP
Synonyms:FETMPYP;FETMPYP PENTACHLORIDE;FE(III)TETRAKIS(1-METHYL-4-PYRIDYL)PORPHYRIN PENTACHLORIDE;FEIIITMPYP(CL);5,10,15,20-TETRAKIS(N-METHYL-4'-PYRIDYL)PORPHINATO IRON (III) CHLORIDE;Fe(III) meso-Tetra (N-Methyl-4-Pyridyl) porphine pentachloride;Iron(III) meso -tetra(N-methyl-4-pyridyl)porphine pentachloride;5,10,15,20-tetra (1-methyl-4-pyridyl) porphyrin ferric chloride
CAS:133314-07-5
MF:C45H62N8
MW:715.02738
EINECS:
Product Categories:
Mol File:133314-07-5.mol
FETMPYP Structure
FETMPYP Chemical Properties
storage temp. Store at -20°C
solubility 0.1 M Tris -HCl, 1 mM EDTA, pH 9.0: >12 mg/ml; PBS pH 7.2: >10.1 mg/ml
form A crystalline solid
color Brown to black
Water Solubility water: 50mg/mL
Safety Information
WGK Germany WGK 1
Storage Class11 - Combustible Solids
MSDS Information
FETMPYP Usage And Synthesis
DescriptionFeTMPyP is a synthetic porphyrin complexed with iron, which acts as a peroxynitrite decomposition catalyst. The rate constant for decomposition of peroxynitrite by FeTMPyP is 2.2 x 106 M−1s−1 with a turnover number of 360 ± 170 s−1. The predominant product (>90%) of this reaction is nitrate, with a minor amount of nitrite also formed (~6%), at pH 7.4.
UsesFeTMPyP is an orally active peroxynitrite (ONOO ) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits[1][2].
References[1] Zhang S, et al. Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging. Oxid Med Cell Longev. 2020 Jan 25;2020:4252047. DOI:10.1155/2020/4252047
[2] Komirishetty P, et al. FeTMPyP a peroxynitrite decomposition catalyst ameliorated functional and behavioral deficits in chronic constriction injury induced neuropathic pain in rats. Free Radic Res. 2021 Oct;55(9-10):1005-1017. DOI:10.1080/10715762.2021.2010731
FETMPYP Preparation Products And Raw materials
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