5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid manufacturers
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| | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid Basic information |
| Product Name: | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid | | Synonyms: | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ,98%;5-Methoxy-6-azaindole-2-carboxylic acid;5-Methoxy-6-azaindole-3-carboxylic acid;1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid, 5-methoxy-;5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid | | CAS: | 17288-36-7 | | MF: | C9H8N2O3 | | MW: | 192.17 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid Structure](StructureFile/ChemBookStructure9/GIF/CB6423449.gif) |
| | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid Chemical Properties |
| Boiling point | 458.4±40.0 °C(Predicted) | | density | 1.459 | | storage temp. | 2-8°C | | pka | 3.21±0.30(Predicted) | | Appearance | White to off-white Solid |
| | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid Usage And Synthesis |
| Chemical Properties | White to grey solid | | Synthesis | GENERAL STEPS: To a stirred solution of ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (1.3 mmol) in ethanol (12 mL) was added 2 M sodium hydroxide solution (1.7 mmol, 1.1 mL). The reaction mixture was heated to reflux for 1 h (for 5-methoxy-1H-pyrrolo[2,3-C]pyridine-2-carboxylic acid) or 2 h (for other derivatives). After completion of the reaction, the solvent was removed by evaporation. Water (10 mL) was added to the residue and the pH was adjusted with acetic acid to 4.0. The precipitate was collected by filtration and the resulting solid was dried in a desiccator to give the target product 5-methoxy-1H-pyrrolo[2,3-C]pyridine-2-carboxylic acid. | | References | [1] Molecules, 2014, vol. 19, # 9, p. 13342 - 13357 |
| | 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid Preparation Products And Raw materials |
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