- Drometrizole
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- $0.00 / 1G/KG
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2026-05-14
- CAS:2440-22-4
- Min. Order: 1G/KG
- Purity: 99%
- Supply Ability: 1000000KG
- Drometrizole
-
- $0.00 / 1KG
-
2026-05-14
- CAS:2440-22-4
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 1000kg/month
Related articles - Risk Assessment of Drometrizole
- UV-P / Drometrizole is an odorless benzotriazole compound that appears as an off-white to yellow crystalline powder.
- Mar 7，2025
- Uses and safety of Drometrizole
- Drometrizole is a benzotriazole derivative used as an ultraviolet (UV) light absorber and stabilizer in cosmetics.
- Jul 19，2022
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| | Drometrizole Chemical Properties |
| Melting point | 125.5-129.5 °C(lit.) | | Boiling point | bp10 225° | | density | 1.38 | | vapor pressure | 0Pa at 20℃ | | refractive index | 1.5600 (estimate) | | Fp | 54°C | | storage temp. | 15-25°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 8.15±0.43(Predicted) | | form | Solid | | color | Off-White to Pale Yellow | | Water Solubility | 173μg/L at 20℃ | | Merck | 14,3447 | | Stability: | Hygroscopic | | Cosmetics Ingredients Functions | UV ABSORBER | | Cosmetic Ingredient Review (CIR) | Drometrizole (2440-22-4) | | InChI | 1S/C13H11N3O/c1-9-6-7-13(17)12(8-9)16-14-10-4-2-3-5-11(10)15-16/h2-8,17H,1H3 | | InChIKey | MCPKSFINULVDNX-UHFFFAOYSA-N | | SMILES | Cc1ccc(O)c(c1)-n2nc3ccccc3n2 | | LogP | 4.2 at 25℃ | | CAS DataBase Reference | 2440-22-4(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-(2440-22-4) | | EPA Substance Registry System | 2-(2H-Benzotriazol-2-yl)-p-cresol (2440-22-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-53-43 | | Safety Statements | 22-24/25-36/37 | | WGK Germany | 1 | | RTECS | GO6860000 | | TSCA | TSCA listed | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Chronic 1
Skin Sens. 1B | | Toxicity | LD50 oral in mouse: 6500mg/kg |
| | Drometrizole Usage And Synthesis |
| Characterization | Drometrizole is an ultraviolet light absorber (UVA) of the hydroxyphenyl benzotriazole class, imparting good light stability to a wide variety of polymers.
| | Applications | Drometrizole provides ultraviolet protection in a wide variety of polymers including styrene homoand copolymers, engineering plastics such as polyesters and acrylic resins, polyvinyl chloride, and other halogen containing polymers and copolymers (e.g. vinylidenes), acetals and cellulose esters. Elastomers, adhesives, polycarbonate blends, polyurethanes, and some cellulose esters and epoxy materials also benefit from the use of Drometrizole.
 | | Features/benefits | Drometrizole features a strong absorption of ultraviolet radiation in the 300-400 nm region. It also has a high degree of photostability over long periods of light exposure. The high absorbance combined with photostability and the ability to release absorbed energy in non sensitizing ways make Drometrizole an effective stabilizer against the effects of ultraviolet light.
| | Guidelines for use | The use levels of Drometrizole range between 0.10% and 0.50%, depending on substrate and performance requirements of the final application. Drometrizole can be used alone or in a variety of blends and combinations with Ciba IRGAFOS®, Ciba IRGANOX® and Ciba CHIMASSORB® stabilizers where often a synergistic performance is observed. Drometrizole may react with various heavy metal ions to form salts or complexes. For example, if Drometrizole comes into contact with iron or cobalt ions, colored complexes are formed. Reducing and oxidizing agents used in polymerization and curing processes have no effect on the stability of Drometrizole.
| | Physical Properties |  | | Safety | In accordance with good industrial practice, handle with care and avoid unnecessary personal contact. Protect skin. Prevent contamination of the environment. Avoid dust formation and ignition sources.
| | Chemical Properties | Light yellow powder | | Uses | Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers. | | Uses | An ultraviolet light absorber for stabilizing plastics and other organic materials against discoloration and deterioration. | | Uses | 2(2-Hydroxy-5-methylphenyl)benzotriazol is an UV adsorber for use in plastics, cosmetics, dental materials, acrylic materials, dyes, etc. | | Definition | Drometrizole is a member of triazoles. | | Application | Intermediate reactant in the synthesis of UV light absorbers for polyester fibers
Reactant for synthesis of:
Benzotriazole UV absorbers with a blocked hydroxy group for us in UV curable paint
Maleimide-bound benzotriazole monomer to use for emulsion polymerization
Used in:
Microstereophotolithography and shape memory alloy for fabrication of miniaturized actuators
PVS and wood / PVC composites as a stabilizer
Acrylonitrile-butadiene-styrene as a UV absorber. | | Flammability and Explosibility | Not classified | | reaction suitability | reaction type: C-C Bond Formation | | Toxicity evaluation | The mutagenicity study of drometrizole was performed using Salmonella typhimurium strains TA1538 and TA98 with metabolic activation in the Ames’ test. Spot test (10 and 100 mg drometrizole/plate) and top agar method (50 and 100 mg drometrizole/plate) were conducted. The results showed that drometrizole was not mutagenic.Mice and rats were administered 5.0 or 10.0 g/kg of drometrizole in sunflower oil by stomach tube intubation. After body weight and behaviour were monitored for 3 weeks, acute toxicity of drometrizole was evaluated to be low. The oral lethal dose (LD50) of drometrizole in mice was reported to be 6.5 g/kg and > 5.0g/kg. Oral toxicity was evaluated in rats for nail care cosmetics containing 1%, 0.3% and 0.03% of drometrizole. The LD50 of products containing 1% of drometrizole was > 15.0 g/kg. The LD50 of products containing 0.3% and 0.03% drometrizole was > 5.0 g/kg. No acute toxicity was observed in these treatments. |
| | Drometrizole Preparation Products And Raw materials |
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