| Company Name: |
shlmai |
| Tel: |
021-67680335 13052188602 |
| Email: |
sale1@shlmai.net |
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| | HUMAN CXCL1 Basic information |
| | HUMAN CXCL1 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | human |
| | HUMAN CXCL1 Usage And Synthesis |
| Biological Activity | GROα, also called CXCL1 (chemokine (C-X-C motif) ligand 1), plays an essential role in neutrophil recruitment, and the initiation of angiogenesis. This gene is up-regulated in multiple cancer types such as, gastric cancer, renal cell carcinoma, prostate cancer and melanoma. The expression of this protein is also elevated in HER2 positive metastatic breast cancer. Its expression is increased in fibroblasts, which might be involved in breast tumor progression, and its stromal expression in breast cancer is linked to poor prognosis. This gene is also up-regulated in the aggressive phenotype of bladder cancer. Polymorphism rs4074 A in this gene is also associated with susceptibility to alcoholic cirrhosis. |
| | HUMAN CXCL1 Preparation Products And Raw materials |
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