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| | Crotonyl fentanyl Basic information |
| Product Name: | Crotonyl fentanyl | | Synonyms: | Crotonyl fentanyl;Crotonyl fentanyl (CRM);2-Butenamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, (2E)-;Crotonyl fentanyl (exempt preparation) | | CAS: | 760930-59-4 | | MF: | C23H28N2O | | MW: | 348.48 | | EINECS: | | | Product Categories: | | | Mol File: | 760930-59-4.mol |  |
| | Crotonyl fentanyl Chemical Properties |
| solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A neat solid |
| DEA Controlled Substances | CSCN: 9844
CSA SCH: Schedule I
NARC: Yes |
| | Crotonyl fentanyl Usage And Synthesis |
| Description | Crotonyl fentanyl is an analytical reference material categorized as an opioid.1,2,3 Crotonyl fentanyl induces generalized responses in mice trained to discriminate oxycodone from saline.4 Crotonyl fentanyl is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications. | | Uses | Crotonyl Fentanyl is an analog of Fentanyl (F274990), which is a controlled substanced used as analgesic. | | References | 1. Eshleman, A.J., Nagarajan, S., Wolfrum, K.M., et al. Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors Biochem. Pharmacol. 182,114293(2020).
2. Vasudevan, L., Vandeputte, M.M., Deventer, M., et al. Assessment of structure-activity relationships and biased agonism at the mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform Biochem. Pharmacol. 177,113910(2020).
3. Varshneya, N.B., Walentiny, D.M., Moisa, L.T., et al. Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances Neuropharmacology 151,171-179(2019).
4. Walentiny, D.M., Moisa, L.T., and Beardsley, P.M. Oxycodone-like discriminative stimulus effects of fentanyl-related emerging drugs of abuse in mice Neuropharmacology 150,210-216(2019). |
| | Crotonyl fentanyl Preparation Products And Raw materials |
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