| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:PF-1163B
CAS:258871-60-2
Package:2500μg/RMB 13100
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PF-1163B manufacturers
- PF-1163B
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- $2720.00 / 2500μg
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2025-12-22
- CAS:258871-60-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | PF-1163B Basic information |
| Product Name: | PF-1163B | | Synonyms: | PF-1163B;(-)-PF1163B;1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)-;3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione | | CAS: | 258871-60-2 | | MF: | C27H43NO5 | | MW: | 461.63 | | EINECS: | | | Product Categories: | | | Mol File: | 258871-60-2.mol |  |
| | PF-1163B Chemical Properties |
| Boiling point | 649.9±50.0 °C(Predicted) | | density | 1.027±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | An oil | | pka | 14.26±0.10(Predicted) |
| | PF-1163B Usage And Synthesis |
| Description | PF-1163B is an antifungal agent produced by Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells. | | Uses | PF-1163B is an antifungal antibiotic[1]. | | Definition | ChEBI: PF 1163B is a macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a pentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. It has a role as an antifungal agent and a Penicillium metabolite. It is a macrolide antibiotic, a lactam and an aromatic ether. | | References | [1] Sasaki T, et al. PF1163A and B, new antifungal antibiotics produced by Penicillium sp. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 2000 Jan;53(1):38-44. DOI:10.7164/antibiotics.53.38 |
| | PF-1163B Preparation Products And Raw materials |
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