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315224-26-1 (free)

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Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:AMG-131 besylate
CAS:849738-78-9
Package:50mg;1980USD|25mg;1520USD|100mg;2500USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:AMG-131 besylate
CAS:849738-78-9
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Email: chenjw@absin.cn
Products Intro:

315224-26-1 (free) manufacturers

  • AMG-131 besylate
  • AMG-131 besylate pictures
  • $1980.00 / 50mg
  • 2025-08-21
  • CAS:849738-78-9
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
315224-26-1 (free) Basic information
Product Name:315224-26-1 (free)
Synonyms:315224-26-1 (free);AMG-131 849738-78-9;AMG-131;AMG-131 besylate
CAS:849738-78-9
MF:C27H18Cl4N2O6S2
MW:672.37
EINECS:
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Mol File:849738-78-9.mol
315224-26-1 (free) Structure
315224-26-1 (free) Chemical Properties
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315224-26-1 (free) Usage And Synthesis
UsesAMG131 (INT131) (benzenesulfonate) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor γ modulator (SPPARM). AMG131 (benzenesulfonate) binds to PPARγ within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 (benzenesulfonate) is promising for research of type-2 diabetes mellitus[1][2][3].
References[1] Linda S Higgins,et al. The Development of INT131 as a Selective PPARgamma Modulator: Approach to a Safer Insulin Sensitizer. PPAR Res. 2008;2008:936906. DOI:10.1155/2008/936906
[2] Alykhan Motani, et al. INT131: a selective modulator of PPAR gamma. J Mol Biol. 2009 Mar 13;386(5):1301-11. DOI:10.1016/j.jmb.2009.01.025
[3] Higgins LS, et al. The Development of INT131 as a Selective PPARgamma Modulator: Approach to a Safer Insulin Sensitizer. PPAR Res. 2008;2008:936906. DOI:10.1155/2008/936906
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