| Company Name: |
Ontores Biotech |
| Tel: |
0571-88760729 18072970094 |
| Email: |
supports@ontorespeptide.com |
|
| | CLIP (86-100) Basic information |
| Product Name: | CLIP (86-100) | | Synonyms: | CLIP (86-100);L-Alanine, L-prolyl-L-valyl-L-seryl-L-lysyl-L-methionyl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-prolyl-L-leucyl-L-leucyl-L-methionyl-L-glutaminyl- | | CAS: | 648881-58-7 | | MF: | C72H128N20O19S3 | | MW: | 1674.1 | | EINECS: | | | Product Categories: | | | Mol File: | 648881-58-7.mol |  |
| | CLIP (86-100) Chemical Properties |
| density | 1.42±0.1 g/cm3(Predicted) | | pka | 3.39±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Pro-Val-Ser-Lys-Met-Arg-Met-Ala-Thr-Pro-Leu-Leu-Met-Gln-Ala |
| | CLIP (86-100) Usage And Synthesis |
| Uses | CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site[1]. | | References | [1] van Luijn MM, et al. Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia. Oncoimmunology. 2015 Jan 7;3(12):e941737. eCollection 2014 Dec. DOI:10.4161/21624011.2014.941737
[2] Thayer WP, et al. Class II-associated invariant chain peptide-independent binding of invariant chain to class II MHC molecules. J Immunol. 1999 Feb 1;162(3):1502-9. PMID:9973407 |
| | CLIP (86-100) Preparation Products And Raw materials |
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