| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
|
| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:HNRNPL antibody Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
|
| Company Name: |
CUSABIO TECHNOLOGY LLC
|
| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:HNRNPL Antibody
|
| Company Name: |
Shanghai Qierqi Biotech Co., Ltd
|
| Tel: |
027-19371278702 18008634902 |
| Email: |
nuodina88@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal HNRNPL Antibody Package:20μl;50μl;100μl
|
| Company Name: |
GeneTex, Inc.
|
| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Products Intro: |
Product Name:hnRNP L antibody
|
| Company Name: |
NSJ Bioreagents
|
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Products Intro: |
Product Name:hnRNP L Antibody
|
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| | HNRNP L ANTIBODY Chemical Properties |
| | HNRNP L ANTIBODY Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | Heterogeneous nuclear ribonucleoprotein L belongs to a family of RNA binding multiprotein complexes that facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP L binds to CA repeat elements to regulate splicing and RNA stability. Binding of hnRNP L has been shown to occur in response to stress stimuli to regulate conformational change and subsequent translation of mRNAs. hnRNPL can promote apoptosis by enhancing translation of p53 mRNA . In the context of tumor progression, hnRNPL has been shown to bind and modify translation of critical regulators of cell cycle and apoptosis. | | References | [1] Piñol-Roma, S. et al. (1989) J Cell Biol 109, 2575-87.
[2] Dreyfuss, G. et al. (1993) Annu Rev Biochem 62, 289-321.
[3] Liu, X. and Mertz, J.E. (1995) Genes Dev 9, 1766-80.
[4] Hui, J. et al. (2003) RNA 9, 931-6.
[5] Hui, J. et al. (2005) EMBO J 24, 1988-98.
[6] Hung, L.H. et al. (2008) RNA 14, 284-96.
[7] Ray, P.S. et al. (2009) Nature 457, 915-9.
[8] Seo, J.Y. et al. (2017) Oncotarget 8, 51108-51122.
[9] Zhou, X. et al. (2017) Oncotarget 8, 19342-19353.
[10] Lv, D. et al. (2017) Oncotarget 8, 13586-13599. |
| | HNRNP L ANTIBODY Preparation Products And Raw materials |
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