205187-53-7
| 中文名称 | 205187-53-7 |
|---|---|
| 中文同义词 | 化合物 T15023;化合物 CX-157 |
| 英文名称 | CX-157 |
| 英文同义词 | CX-157;Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide;CX 157,CX157;3-Fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiine 10,10-dioxide |
| CAS号 | 205187-53-7 |
| 分子式 | C14H8F4O4S |
| 分子量 | 348.27 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 205187-53-7.mol |
| 结构式 |  |
205187-53-7 性质
| 沸点 | 430.0±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.549±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
CX-157 是一个可逆的单胺氧化酶-A (MAO-A) 抑制剂，其 EC50 值为 19.3 ng/mL。
EC50: 19.3 ng/mL (MAO-A)
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC 50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters.