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BOC Sciences |
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| | Rifalogue Basic information |
| Product Name: | Rifalogue | | Synonyms: | Rifalogue;Rifamycin VIII, 1',4-didehydro-1-deoxy-5'-[4-(dimethylamino)-1-piperidinyl]-1,4-dihydro-3'-hydroxy-1-oxo-;dmDNA31 | | CAS: | 845625-44-7 | | MF: | C50H62N4O13 | | MW: | 927.06 | | EINECS: | | | Product Categories: | | | Mol File: | 845625-44-7.mol |  |
| | Rifalogue Chemical Properties |
| Boiling point | 1067.8±65.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 4.28±0.70(Predicted) | | form | Solid | | color | Purple to black |
| | Rifalogue Usage And Synthesis |
| Uses | dmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S. aureus[1]. | | References | [1] Peck M, et al. A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti-Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers. Antimicrob Agents Che DOI:10.1128/AAC.02588-18 |
| | Rifalogue Preparation Products And Raw materials |
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