- Atractylon
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- $0.00 / 20mg
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2023-02-24
- CAS:6989-21-5
- Min. Order: 20mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | ATRACTYLON Basic information |
| Product Name: | ATRACTYLON | | Synonyms: | Atractyline;ATRACTYLINE(DISCONTINUED)(SH);(4aS)-4,4aα,5,6,7,8,8a,9-Octahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan;(4aS,8aR)-3,8a-diMethyl-5-Methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan;Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-diMethyl-5-Methylene-, (4aS,8aR)-;(4aS,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan;ATRACTYLON | | CAS: | 6989-21-5 | | MF: | C15H20O | | MW: | 216.32 | | EINECS: | | | Product Categories: | Heterocycles | | Mol File: | 6989-21-5.mol |  |
| | ATRACTYLON Chemical Properties |
| Melting point | 61-63℃ | | Boiling point | 287.1±19.0℃ (760 Torr) | | density | 1.02±0.1 g/cm3 (20 ºC 760 Torr) | | Fp | 121.7±8.3℃ | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Soild | | color | Faint red to very dark red | | InChI | InChI=1S/C15H20O/c1-10-5-4-6-15(3)8-14-12(7-13(10)15)11(2)9-16-14/h9,13H,1,4-8H2,2-3H3/t13-,15+/m0/s1 | | InChIKey | TYPSVDGIQAOBAD-DZGCQCFKSA-N | | SMILES | O1C=C(C)C2C[C@]3([H])[C@@](C)(CC1=2)CCCC3=C | | LogP | 5.570 |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | ATRACTYLON Usage And Synthesis |
| Chemical Properties | Yellow liquid, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Atractylodes macrocephala and Atractylodes lancea. | | Uses | Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2]. | | Definition | ChEBI: Atractylone is a sesquiterpenoid. | | Biological Activity | Atractylon is a main active component of Atractylodis Rhizoma th at exhibits antibacterial, antiviral, anti-inflammatory, anti-allergic, anticancer, gastroprotective and neuroprotective activities. Atractylon inhibits proliferation, induces apoptosis and blocks invasion in varies hepatic cancer cell lines. It inhibits the expression of Bcl-2 and promotes the expression of Bax. | | target | IL Receptor | VEGFR | Histamine Receptor | | References | [1] Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. DOI:10.3892/mmr.2016.5713
[2] Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68. DOI:10.1016/j.cbi.2016.08.015 |
| | ATRACTYLON Preparation Products And Raw materials |
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