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| Product Name: | A85380 | | Synonyms: | A85380;Pyridine, 3-(2-azetidinylMethoxy)-, (S)-;(S)-3-(2-Azetidinylmethoxy)pyridine;Pyridine, 3-[(2S)-2-azetidinylmethoxy]- | | CAS: | 161416-98-4 | | MF: | C9H12N2O | | MW: | 164.2 | | EINECS: | | | Product Categories: | | | Mol File: | 161416-98-4.mol |  |
| | A85380 Chemical Properties |
| Boiling point | 283.7±10.0 °C(Predicted) | | density | 1.096±0.06 g/cm3(Predicted) | | solubility | H2O: 10 mg/mL | | form | solid | | pka | 10.15±0.40(Predicted) | | color | off-white |
| | A85380 Usage And Synthesis |
| Uses | A 85380 is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. A 85380 exhibits selectivity for the α4β2 nAChR subtypes. A 85380 has a broad-spectrum analgesic profile[1]. | | References | [1] Sullivan J P, et al. A-85380 [3-(2 (S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand[J]. Neuropharmacology, 1996, 35(6): 725-734. |
| | A85380 Preparation Products And Raw materials |
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