Propargyl-PEG12-N3 manufacturers
- Propargyl-PEG12-N3
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2025-06-07
- CAS:2264091-72-5
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | Propargyl-PEG12-N3 Basic information |
| Product Name: | Propargyl-PEG12-N3 | | Synonyms: | Propargyl-PEG12-N3;3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacont-38-yne, 1-azido-;Azido-PEG12-propargyl;Alkyne-PEG12-N3;1-Azido-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacont-38-yne | | CAS: | 2264091-72-5 | | MF: | C27H51N3O12 | | MW: | 609.71 | | EINECS: | | | Product Categories: | | | Mol File: | 2264091-72-5.mol |  |
| | Propargyl-PEG12-N3 Chemical Properties |
| | Propargyl-PEG12-N3 Usage And Synthesis |
| Uses | Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014. DOI:10.1016/j.chembiol.2020.07.020 |
| | Propargyl-PEG12-N3 Preparation Products And Raw materials |
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