2’-Deoxy-2’-fluoro-5-methyl-4’-thio-beta-D-arabinouridine
| 中文名称 | 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-beta-D-arabinouridine |
|---|---|
| 中文同义词 | 化合物 2'-DEOXY-2'-FLUORO-5-METHYL-4'-THIO-BETA-D-ARABINOURIDINE |
| 英文名称 | 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-beta-D-arabinouridine |
| 英文同义词 | 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-beta-D-arabinouridine;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-5-methyl-;2’-Deoxy-2’-fluoro-5-methyl-4’-thio-b-D-arabino uridine;1-((2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione |
| CAS号 | 135123-34-1 |
| 分子式 | C10H13FN2O4S |
| 分子量 | 276.28 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 135123-34-1.mol |
| 结构式 |  |
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-beta-D-arabinouridine 性质
| 密度 | 1.58±0.1 g/cm3(Predicted) |
|---|---|
| 酸度系数(pKa) | 9.55±0.10(Predicted) |
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。