2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide

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2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide Basic information
Product Name:2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide
Synonyms:2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide;2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin;2H-1,3,2-Oxazaphosphorine, 2-chlorotetrahydro-, 2-oxide;Ifosfamide Impurity 6
CAS:5638-58-4
MF:C3H7ClNO2P
MW:155.52
EINECS:
Product Categories:
Mol File:5638-58-4.mol
2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide Structure
2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide Chemical Properties
Melting point 79-82 °C
Boiling point 195.8±23.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
pka-1.45±0.20(Predicted)
Safety Information
MSDS Information
2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide Usage And Synthesis
Uses2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin is an intermediate in the synthesis of N-Dides(2-chloroethyl) N-(2-Hydroxyethyl),N-(2-ethoxyethyl) Cyclophosphamide (C984610) which is a derivative ofCyclophosphamide Monohydrate (C988580), a known human carcinogen that is widely used in cancer chemotherapy because it can cross-link DNA causing strand breakage and mutation.
2-Chloro-1,3,2-oxazaphosphacyclohexane 2-oxide Preparation Products And Raw materials
Preparation ProductsIfosfamide impurity F
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