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| | Octanoyl Coenzyme A (sodium salt) Basic information |
| | Octanoyl Coenzyme A (sodium salt) Chemical Properties |
| solubility | Ethanol: Partially solublePBS (pH 7.2): 10 mg/ml |
| | Octanoyl Coenzyme A (sodium salt) Usage And Synthesis |
| Description | Octanoyl-coenzyme A (octanoyl-CoA) is a medium-chain acyl CoA and a metabolic intermediate in mitochondrial fatty acid β-oxidation. Levels of octanoyl-CoA are increased in the liver of patients with Reye’s syndrome and β-oxidation of octanoyl-CoA by medium-chain acyl CoA dehydrogenase (MCADH) is decreased in patients with MCADH deficiency (MCD). Octanoyl-CoA inhibits citrate synthase and glutamate dehydrogenase. | | References | [1] J C LAI. Differential effects of fatty acyl coenzyme A derivatives on citrate synthase and glutamate dehydrogenase.[J]. Research communications in chemical pathology and pharmacology, 1993, 82 3: 331-338.
[2] B E CORKEY. Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome.[J]. Journal of Clinical Investigation, 1988, 82 3: 782-788. DOI: 10.1172/jci113679
[3] B A AMENDT W J R. Catalytic defect of medium-chain acyl-coenzyme A dehydrogenase deficiency. Lack of both cofactor responsiveness and biochemical heterogeneity in eight patients.[J]. Journal of Clinical Investigation, 1985, 76 3: 963-969. DOI: 10.1172/jci112096 |
| | Octanoyl Coenzyme A (sodium salt) Preparation Products And Raw materials |
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