2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran

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2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran manufacturers

  • Br-PEG2-THP
  • Br-PEG2-THP pictures
  • 2025-06-07
  • CAS:152065-54-8
  • Min. Order: 1g
  • Purity: >98.00%
  • Supply Ability: 1g
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran Basic information
Product Name:2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran
Synonyms:2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran;Br-PEG2-THP;2H-Pyran, 2-[2-(2-bromoethoxy)ethoxy]tetrahydro-;2-[2-(2-bromoethoxy)ethoxy]oxane;N-(2-chlorophenyl)-2-{[5-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-yl]sulfanyl}acetamide;THP-PEG2-bromide
CAS:152065-54-8
MF:C9H17BrO3
MW:253.13
EINECS:
Product Categories:
Mol File:152065-54-8.mol
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran Structure
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran Chemical Properties
Boiling point 314.3±37.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
Safety Information
MSDS Information
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran Usage And Synthesis
UsesBromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological ActivityBromo-PEG2-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50PEGs
References[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran Preparation Products And Raw materials
Tag:2-[2-(2-Bromoethoxy)ethoxy]tetrahydro-2H-pyran(152065-54-8) Related Product Information
Br-PEG5-THP 2H-Pyran, 2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]tetrahydro- Br-PEG6-Ms 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Br-PEG9-Ms Br-PEG3-MS Br-PEG9-THP Br-PEG7-THP Br-PEG8-Ms Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1-methanesulfonate Br-PEG5-Ms Ethanol, 2-(2-bromoethoxy)-, 1-methanesulfonate Br-PEG6-THP Br-PEG7-Ms Methanesulfonic acid 2-bromoethyl ester Br-PEG8-THP 2-(2-Bromoethoxy)tetrahydro-2H-pyran Br-PEG10-Ms