| Company Name: |
Fedprotein |
| Tel: |
13041401126; 13041401126 |
| Email: |
3690410801@qq.com |
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| Product Name: | NRBF2 antibody | | Synonyms: | NRBF2 antibody;Mouse Monoclonal NRBF2 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![NRBF2 antibody Structure]() |
| | NRBF2 antibody Chemical Properties |
| | NRBF2 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | Nuclear Receptor Binding Factor-2, also referred to as Comodulator of PPAR and RXRα-2, has been shown to interact with the AF-2 region of several nuclear hormone receptors with varying affinities such as PPARα, RARα, RARγ, and RXRα. NRBF-2 contains a LLYLL motif, which matches the LXXLL NR box consensus and is required for functional NRBF-2/nuclear receptor complex formation and repression of receptor function. NRBF-2 also contains a unique autonomous activation domain and, thus, does not completely abrogate nuclear receptor function, suggesting that NRBF-2 might serve as a molecular rheostat to fine-tune the transcriptional activity of liganded nuclear receptors. | | References | [1] Yasumo, H. et al. (2000) Biochim Biophys Acta 1490, 189-97.
[2] Flores, A.M. et al. (2004) J Invest Dermatol 123, 1092-101. |
| | NRBF2 antibody Preparation Products And Raw materials |
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