1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone

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1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone Basic information
Product Name:1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone
Synonyms:1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone;Ethanone, 1-(2,5-dihydroxy-4-methoxyphenyl)-
CAS:22089-12-9
MF:C9H10O4
MW:182.17
EINECS:
Product Categories:
Mol File:22089-12-9.mol
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone Structure
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone Chemical Properties
Melting point 166–167°C
Safety Information
MSDS Information
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone Usage And Synthesis
Uses2,5-Dihydroxy-4-methoxyacetophenone (compounds 3) can be isolated from the 80% methanol extract of roots of Cynanchum paniculatum Kitagawa. 2,5-Dihydroxy-4-methoxyacetophenone inhibits glutamate-induced cytotoxicity in hippocampal HT22 cell line[1].
PreparationPreparation by Fries rearrangement of 2-methoxyhydroquinone diacetate, with boron trifluoride in acetic acid (97%); with aluminium chloride in nitrobenzene at r.t., (38%).
References[1] Jin Bae Weon, et al. Neuroprotective compounds isolated from Cynanchum paniculatum. Arch Pharm Res. 2012, 35, 4. DOI:10.1007/s12272-012-0404-4
1-(2,5-Dihydroxy-4-methoxyphenyl)ethanone Preparation Products And Raw materials
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