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| | Fibrinopeptide A, human (TFA) Basic information |
| | Fibrinopeptide A, human (TFA) Chemical Properties |
| form | Solid | | color | White to off-white | | Sequence | H-Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH |
| | Fibrinopeptide A, human (TFA) Usage And Synthesis |
| Uses | Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1]. | | in vivo | Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. | | References | [1] Riedel T, et al. Fibrinopeptides A and B release in the process of surface fibrin formation. Blood. 2011 Feb 3;117(5):1700-6. DOI:10.1182/blood-2010-08-300301
[2] Manolis AS, et al. Plasma level changes of fibrinopeptide A after uncomplicated coronary angioplasty. Clin Cardiol. 1993 Jul;16(7):548-52. DOI:10.1002/clc.4960160707 |
| | Fibrinopeptide A, human (TFA) Preparation Products And Raw materials |
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