| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:BLX3887
CAS:934758-70-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:BLX3887
CAS:934758-70-0
Package:1removed
|
|
| | BLX3887 Basic information |
| Product Name: | BLX3887 | | Synonyms: | BLX3887;1H-Pyrazole-3-carboxamide, 4,5-dichloro-N-(2-chloro-4-fluorophenyl)-;4,5-dichloro-N-(2-chloro-4-fluorophenyl)-1H-pyrazole-3-carboxamide | | CAS: | 934758-70-0 | | MF: | C10H5Cl3FN3O | | MW: | 308.52 | | EINECS: | | | Product Categories: | | | Mol File: | 934758-70-0.mol |  |
| | BLX3887 Chemical Properties |
| Boiling point | 395.4±42.0 °C(Predicted) | | density | 1.714±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml | | form | A crystalline solid | | pka | 7.07±0.50(Predicted) |
| | BLX3887 Usage And Synthesis |
| Description | BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over neutrophils when used at a concentration of 10 µM. It also inhibits endocytosis in, and the migration of, isolated human peripheral blood mononuclear cell-derived dendritic cells in vitro.WARNING This product is not for human or veterinary use. |
| | BLX3887 Preparation Products And Raw materials |
|