- 4-Methoxy-1-indanone
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- $1.60 / 100kg
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2025-10-13
- CAS:13336-31-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
- 4-METHOXY-1-INDANONE
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- $0.00 / 1kg
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2025-04-04
- CAS:13336-31-7
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
- 4-METHOXY-1-INDANONE
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- $1.00 / 1KG
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2019-07-12
- CAS:13336-31-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | 4-METHOXY-1-INDANONE Basic information |
| | 4-METHOXY-1-INDANONE Chemical Properties |
| Melting point | 105-107 °C (dec.) (lit.) | | Boiling point | 115-120 °C/0.5 mmHg (lit.) | | density | 1.0281 (rough estimate) | | refractive index | 1.6000 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | Appearance | Off-white to light yellow Solid | | InChI | InChI=1S/C10H10O2/c1-12-10-4-2-3-7-8(10)5-6-9(7)11/h2-4H,5-6H2,1H3 | | InChIKey | BTYSYELHQDGJAB-UHFFFAOYSA-N | | SMILES | C1(=O)C2=C(C(OC)=CC=C2)CC1 | | CAS DataBase Reference | 13336-31-7(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2914500090 |
| | 4-METHOXY-1-INDANONE Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 4-Methoxy-1-indanone is suitable for use in the comparative study of the effect of different substituents on various benzo-fused ketones on the reaction kinetics by studying the biocatalysed oxidation reaction.
It may be used in the following studies:
- Synthesis of isomeric mixture of oximes.
- As a starting material in the synthesis of benzo-fused indolizidine and 4-methoxy-1-indanyl compound.
- Synthesis of 4-methoxy-5-nitro-1-indanone by nitration reaction.
- As one of the reactant in the synthesis of E-2-chloro-8-methyl-3-[(4′-methoxy-1′-indanoyl)-2′-methyliden]-quinoline (IQ), a quinoline derivative.
| | General Description | 4-Methoxy-1-indanone, a benzo-fused ketone is a 1-indanone derivative. Its synthesis has been reported. | | Synthesis | The reaction was carried out with 4-hydroxy-1-indanone (125 mg) and iodomethane (263 μL) in the presence of potassium carbonate (350 mg) in N,N-dimethylformamide (DMF, 4 mL) for 3 h at 50 °C with stirring. After completion of the reaction, the mixture was poured into 1N hydrochloric acid (20 mL) and extracted with ether (4 × 10 mL). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to give 4-methoxy-1-indanone intermediate as a clear oil (131 mg, 96% yield). Mass spectral analysis showed [MH]+ = 163. | | References | [1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 9, p. 1756 - 1759
[2] Patent: US2006/173183, 2006, A1. Location in patent: Page/Page column 114
[3] European Journal of Medicinal Chemistry, 2013, vol. 69, p. 920 - 930
[4] Patent: WO2014/19344, 2014, A1. Location in patent: Paragraph 00821
[5] Patent: WO2014/82380, 2014, A1. Location in patent: Paragraph 00314; 00316 |
| | 4-METHOXY-1-INDANONE Preparation Products And Raw materials |
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