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| | Potassium trimethylsilanolate Basic information |
| Product Name: | Potassium trimethylsilanolate | | Synonyms: | Trimethylsiloxypotassium;potassium trimethylsilanolate,2M in tetrahydrofuran;(Potassiooxy)trimethylsilane;(Trimethylsilyloxy) potassium;Potassiooxytrimethylsilane;Trimethyl(potassiooxy)silane;Potassium trimethylsilanolate,Trimethylsilanol potassium salt;PotassiuM triMethyl silanolate LR grade | | CAS: | 10519-96-7 | | MF: | C3H9KOSi | | MW: | 128.29 | | EINECS: | 234-062-7 | | Product Categories: | | | Mol File: | 10519-96-7.mol |  |
| | Potassium trimethylsilanolate Chemical Properties |
| Melting point | 135-138 °C (lit.) | | density | 0.91 | | Fp | -14°C (7°F) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Springly), Methanol (Slightly) | | form | powder | | Specific Gravity | 0.91 | | color | White | | Hydrolytic Sensitivity | 7: reacts slowly with moisture/water | | BRN | 3560282 | | InChI | InChI=1S/C3H9OSi.K/c1-5(2,3)4;/h1-3H3;/q-1;+1 | | InChIKey | LBKJNHPKYFYCLL-UHFFFAOYSA-N | | SMILES | [Si]([O-])(C)(C)C.[K+] | | EPA Substance Registry System | Silanol, trimethyl-, potassium salt (10519-96-7) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3263 8/PG 2 | | WGK Germany | 3 | | F | 3-10-21 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29319090 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Skin Corr. 1B |
| | Potassium trimethylsilanolate Usage And Synthesis |
| Chemical Properties | Potassium trimethylsilanolate is a white solid with slight odor, decomposes above 134 °C.
| | Uses |
Potassium trimethylsilanolate can be used as a reagent in the:
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Hydrolysis of nitriles to primary amides.
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Conversion of esters to carboxylic acids, and dialkyl phosphonates to their monoalkyl phosphonates.
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Synthesis of E-alkenes, and nitrocefin.
It can also be used as a coupling promoter in cross-coupling reaction of aliphatic alkynylsilanols with aryl iodides.
| | Production Methods |
109 kg of hexamethyldichlorosilane was put into a stirring kettle, and nitrogen was introduced at a flow rate of 1 L/min for 0.5 h while stirring. 56 kg of potassium hydroxide was added while stirring. After returning water at 100° C. for 10 h, the material was discharged into a centrifugal spray drying oven and centrifuged and spray-dried at 3000 rpm and 100° C. for 5 h to obtain white crystalline potassium trimethylsilanol with a purity of 99.99%.
| | Solubility in organics | Potassium trimethylsilanolate is solubility in tetrahydrofuran, diethyl ether, toluene, dichloromethane, alcohols, and most other organic solvents. | | Purification Methods | Recrystallise it from H2O and dry it at 100o/1-2mm. [Hyde et al. J Am Chem Soc 75 5615 1953, IR: Tatlock & Rochow J Org Chem 17 1555 1952, Beilstein 4 IV 3992.] | | References | [1] C. A., 1949, p. 7500
[2] Journal of the American Chemical Society,
[3] Journal of the American Chemical Society, 1953, vol. 75, p. 5615 - 5618
[4] , Gmelin Handbook: Si: MVol.C, 84, page 231 - 233,
[5] Patent: US2472799, 1946, |
| | Potassium trimethylsilanolate Preparation Products And Raw materials |
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