Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester manufacturers
- cjoc42
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- $58.00
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2026-07-15
- CAS:2171519-89-2
- Purity: 99.56%
- Supply Ability: 10g
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| | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester Basic information |
| Product Name: | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester | | Synonyms: | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester;inhibit,transcription,p53,gankyrin,Inhibitor,DNA damage,cjoc42,MDM-2/p53;Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate;cjoc42, 10 mM in DMSO | | CAS: | 2171519-89-2 | | MF: | C20H21N3O5S | | MW: | 415.46 | | EINECS: | | | Product Categories: | | | Mol File: | 2171519-89-2.mol | ![Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester Structure](CAS/20200611/GIF/2171519-89-2.gif) |
| | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester Chemical Properties |
| Boiling point | 616.3±65.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | pka | -0.06±0.70(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester Usage And Synthesis |
| Uses | Cjoc42 is a compound capable of binding to gankyrin. Cjoc42 inhibits gankyrin activity in a dose-dependent manner. Cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin. Cjoc42 restores p53-dependent transcription and sensitivity to DNA damage[1]. | | References | [1] Chattopadhyay A, et al. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016;6:23732. DOI:10.1038/srep23732 |
| | Benzoic acid, 4-[4-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-1H-1,2,3-triazol-1-yl]-, methyl ester Preparation Products And Raw materials |
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