(+)-Lupanine perchlorate manufacturers
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| | (+)-Lupanine perchlorate Basic information |
| Product Name: | (+)-Lupanine perchlorate | | Synonyms: | (+)-Lupanine perchlorate;(7S,7aR,14S,14aS)-dodecahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1′,2′-e][1,5]diazocin-11-one, monoperchlorate | | CAS: | 7400-11-5 | | MF: | C15H25ClN2O5 | | MW: | 348.82 | | EINECS: | | | Product Categories: | | | Mol File: | 7400-11-5.mol |  |
| | (+)-Lupanine perchlorate Chemical Properties |
| Melting point | 204-205 °C | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Very Slightly, Sonicated) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic |
| | (+)-Lupanine perchlorate Usage And Synthesis |
| Uses | (+)-Lupanine is used in biological studies with quinolizidine alkaloids in seeds of lupin genotypes of different origins. | | in vivo | Lupanine (100-300 mg/kg for i.p.; 175-700 mg/kg for p.o.) is much less toxic in one single injection in EOPS male Swiss mice (20-22 g) and Hartley guinea-pigs (400-500 g)[1].
Lupanine (1-7.5 mg/kg; i.v.) is more efficient than Sparteine for antagonizing secondary reflex hypertension in carotid occlusion and hypotension resulting from the stimulation of the pneumogastric nerve in both the cat and the dog[1].
Lupanine has an inhibitory action on nicotinic type hypertension produced by injection of Acetylcholine (500 p.g/kg i.v.) in the Atropine-treated dog[1].
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| | (+)-Lupanine perchlorate Preparation Products And Raw materials |
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