2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-

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2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- Basic information
Product Name:2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-
Synonyms:2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-
CAS:350509-85-2
MF:C13H12N2O4S
MW:292.31
EINECS:
Product Categories:
Mol File:350509-85-2.mol
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- Structure
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- Chemical Properties
Boiling point 474.0±55.0 °C(Predicted)
density 1.518±0.06 g/cm3(Predicted)
pka8.48±0.10(Predicted)
Safety Information
MSDS Information
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- Usage And Synthesis
UsesERK1/2 inhibitor 12 (compound 76.3) is a ERK1/2 inhibitor which inhibits ERK-mediated phosphorylation of caspase-9 and the p90Rsk-1 kinase. ERK1/2 inhibitor 12 exhibits anti-cancer activity and can be utilized in cancer research[1].
References[1] Boston SR, et al. Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer. 2011 Jan 10;11:7. DOI:10.1186/1471-2407-11-7
2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)- Preparation Products And Raw materials
Tag:2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-(1,3-benzodioxol-5-ylmethylene)-(350509-85-2) Related Product Information
N-[2-[(5Z)-5-(1,3-Benzodioxol-5-ylmethylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]-2-chloroacetamide 2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-[(3,4-dimethoxyphenyl)methylene]- 2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-[(4-ethoxy-3-methoxyphenyl)methylene]- 3-(2-Aminoethyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione 2,4-Thiazolidinedione, 3-(2-aminoethyl)-5-[(4-ethoxy-3-methoxyphenyl)methylene]-, hydrochloride (1:1) (5E)-3-(2-aminoethyl)-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione hydrochloride