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| | Pyrazolo[1,5-a]pyridine Basic information |
| Product Name: | Pyrazolo[1,5-a]pyridine | | Synonyms: | 6,7a-dimethyl-2,3,5,6-tetrahydrooxazolo[2,3-b]oxazole;PYRAZOLO[1,5-A]PYRIDINE;3-Azaindoline;1H-Pyrazolo[1,5-a]pyridine;Pyrazolo[1,5-a]pyridine,97% | | CAS: | 274-56-6 | | MF: | C7H6N2 | | MW: | 118.14 | | EINECS: | | | Product Categories: | | | Mol File: | 274-56-6.mol | ![Pyrazolo[1,5-a]pyridine Structure](CAS/GIF/274-56-6.gif) |
| | Pyrazolo[1,5-a]pyridine Chemical Properties |
| Boiling point | 37-39℃/0.2mm | | density | 1.14±0.1 g/cm3(Predicted) | | refractive index | 1.6075 | | storage temp. | Sealed in dry,Room Temperature | | form | Liquid | | pka | 2.83±0.30(Predicted) | | color | Colorless to red or brown |
| | Pyrazolo[1,5-a]pyridine Usage And Synthesis |
| Description |
Pyrazolo[1,5-a]pyridines, a class of fused heteroaromatic bicyclic compounds, have been investigated for their pharmacological and biological activities. They are used as dopamine D2/D3/D4 antagonists, anti-herpetic agents, p38 kinase inhibitors, PI3 kinase inhibitors, antitubercular agents, EP1 receptor antagonists, 5HT3-antagonists, melatonin receptor (MT1/MT2) ligands, Mcl-1Bcl-xL dual inhibitors, and corticotropin-releasing factor 1 antagonists. Pyrazolo[1,5-a]pyridine has been used as a fluorophore in the research of Zhang et al. and exhibited high quantum yield (0.64, pH 2.4), high selectivity and sensitivity, and extremely short response time[1].
| | References | [1] Brian A Johns. “Pyrazolo[1,5-a]pyridines: synthetic approaches to a novel class of antiherpetics.” Tetrahedron 59 45 (2003): Pages 9001-9011.
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| | Pyrazolo[1,5-a]pyridine Preparation Products And Raw materials |
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