[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide

Request For Quotation
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Suppliers list
Company Name: Shanghai Kewel Chemical Co., Ltd.  
Tel: 021-64609169 18901607656
Email: greensnown@163.com
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Email: marketing@energy-chemical.com
Company Name: Hubei Moco Chemical Co., Ltd.  
Tel: 18627753421; 18627756402
Email: 3001051413@qq.com
Company Name: LGC Science (Shanghai) Ltd.  
Tel: 17717235263 17717235263
Email: offer.de@lgcgroup.com
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Basic information
Product Name:[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide
Synonyms:[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide;(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one;Desmethylnarcotine;(3S)-3-[(5R)-4-hydroxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-dimethoxy-3H-2-benzofuran-1-one;(3S)-3-[(5R)-4-hydroxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-dimethoxy-3H-isobenzofuran-1-one;narcotoline;Noscapine Impurity 6(Narcotoline);1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
CAS:521-40-4
MF:C21H21NO7
MW:399.39
EINECS:208-313-6
Product Categories:
Mol File:521-40-4.mol
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Structure
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Chemical Properties
Melting point 202°
alpha D20 -189° (0.1 g in 25 ml chloroform, 20 cm tube); D20 +5.8° (0.065 g in 5 ml 0.1N HCl in 20 cm tube)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color Pale Yellow to Light Yellow
Safety Information
MSDS Information
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Usage And Synthesis
DescriptionWrede has obtained this alkaloid from the seed capsules of Papaver somniferum. It crystallizes from aqueous MeOH in colourless rectangular rods and has [0:]5° - 189° (CHCI3) and + 5.8° (c 0.1 NiHCI). One phenolic hydroxyl group is present in the molecule and the base forms the O-acetate, m.p. 208-9°C, giving a hydro_x0002_chloride as the monohydrate, m.p. 230-3°C (dry); [0:]5° + 94.8° (H 20). The acid tartrate forms colourless needles which, decompose at 190-205°C and the picrolonate has m.p. 202-3°C. On treatment with CH2N2, the alkaloid gives Narcotine (q.v.).
UsesDesmethylnarcotine is an impurity of Narcotoline an opiate alkaloid and a structure analogue of Nascapine (N882000), an antitussive agent. Noscapine (N882000) metabolite.
DefinitionChEBI: Narcotoline is a member of isoquinolines.
ReferencesWrede., r;hem. Zentr., I, 2611 (1937)
Wrede., ibid, II, 863 (1938)
[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide Preparation Products And Raw materials
Tag:[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide(521-40-4) Related Product Information