Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine

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Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine manufacturers

  • Et-29
  • Et-29 pictures
  • $63.00
  • 2026-07-15
  • CAS:2166487-23-4
  • Purity: 99.52%
  • Supply Ability: 10g
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine Basic information
Product Name:Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine
Synonyms:Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine;NRD167;ethyl (5S)-5-((1H-indol-3-yl)methyl)-8-(((benzyloxy)carbonyl)amino)-2-methyl-4,7-dioxo-14-thioxo-3,6,13,15-tetraazaoctadecan-18-oate;Et-29;Et-29, 10 mM in DMSO
CAS:2166487-23-4
MF:C34H46N6O6S
MW:666.83
EINECS:
Product Categories:
Mol File:2166487-23-4.mol
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine Structure
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine Chemical Properties
density 1.225±0.06 g/cm3(Predicted)
storage temp. Store at -20°C, protect from light, stored under nitrogen
solubility DMSO: 2mg/mL, clear
pka11.08±0.46(Predicted)
form powder
color white to beige
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine Usage And Synthesis
UsesEt-29 is a potent and selective SIRT5 inhibitor (Ki=40 nM)[1].
Biological ActivityEt-29 is a potent and selective SIRT5 inhibitor (Ki=40 nM)[1].
IC 50SIRT5: 40 nM (Ki)
References[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017;56(47):14836-14841.
Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine Preparation Products And Raw materials
Tag:Z-Lys（thiourea-beta-Ala-OEt）-Trp-Isopropylamine(2166487-23-4) Related Product Information
Z-D-Trp-Leu-OH Z-Trp-Gly-OH Carbobenzyloxy-L-isoleucyl-L-tryptophan methyl ester L-Phenylalaninamide, N-[(phenylmethoxy)carbonyl]-L-tryptophyl- 3-(4-hydroxyphenyl)-2-[[3-(1H-indol-3-yl)-2-phenylmethoxycarbonylamino-propanoyl]amino]propanoic acid N-t-Boc-Gly-Trp-Met-Asp(benzyl)-pheamide)