4-Amino-2,5,6-trichloropyrimidine manufacturers
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| | 4-Amino-2,5,6-trichloropyrimidine Basic information |
| Product Name: | 4-Amino-2,5,6-trichloropyrimidine | | Synonyms: | 4-Amino-2,5,6-Trichloropyrimidine;2,5,6-TrichloropyriMidin-4-aMine;2,5,6-Trichloro-pyrimidin-4-ylamine;2,5,6-trichloro-4-pyrimidinamine;4-Pyrimidinamine, 2,5,6-trichloro- | | CAS: | 28969-60-0 | | MF: | C4H2Cl3N3 | | MW: | 198.44 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 28969-60-0.mol |  |
| | 4-Amino-2,5,6-trichloropyrimidine Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | Appearance | White to off-white Solid |
| | 4-Amino-2,5,6-trichloropyrimidine Usage And Synthesis |
| Synthesis | The general procedure for the synthesis of 4-amino-2,5,6-trichloropyrimidine from 4-amino-2,6-dichloropyrimidine was as follows: 1 g (6.1 mmol) of 4-amino-2,6-dichloropyrimidine was dissolved in 5 ml of N,N-dimethylformamide (DMF). To this solution 0.98 g (7.32 mmol) of N-chlorosuccinimide (NCS) was added. The reaction mixture was poured into 100 ml of ice water. The precipitate formed was collected by filtration, washed several times with distilled water and dried under vacuum to give 1.4 g (80% yield) of the target product as a white solid. The structure of the product was confirmed by 1H nuclear magnetic resonance (NMR) spectrum (300 MHz, DMSO-d6): δ= 8.24 (d, 2H). | | References | [1] Patent: WO2011/121418, 2011, A1. Location in patent: Page/Page column 24-25 |
| | 4-Amino-2,5,6-trichloropyrimidine Preparation Products And Raw materials |
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