| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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| Tel: |
021-61312847; 18021002903 |
| Email: |
3008007409@qq.com |
| Products Intro: |
Product Name:XIAP Antibody
Purity:无载体, 无叠氮钠, 已验证, 高性能, 见COA Package:10μl;50μl;100μl;1ml Remarks:K10592
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| Company Name: |
Shanghai Universal Biotech Co.,Ltd
|
| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:XIAP Antibody
Package:100ul Remarks: 见优宁维官网
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| Company Name: |
Shanghai Aladdin Biochemical Technology Co.,Ltd.
|
| Tel: |
6206333 13167063860 |
| Email: |
anhua.mao@aladdin-e.com |
| Products Intro: |
Product Name:XIAP Antibody
Purity:无载体, ExactAb?, 无叠氮钠, 已验证, 高性能, 见COA Package:10μl/RMB 339.90;50μl/RMB 999.90;100μl/RMB 1609.90
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| Company Name: |
Novus Biologicals
|
| Tel: |
400821347 |
| Email: |
orders@novusbio.com |
| Products Intro: |
Product Name:XIAP Antibody
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| Company Name: |
CUSABIO TECHNOLOGY LLC
|
| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:XIAP Antibody
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| | XIAP Antibody Chemical Properties |
| | XIAP Antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Mouse;Rat;Monkey;Human | | Background | The inhibitor of apoptosis protein family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 amino acid BIR domain. Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression. In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9. In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with caspase-9, thereby allowing the processing and activation of the caspase. | | References | [1] Deveraux, Q.L. and Reed, J.C. (1999) Genes Dev 13, 239-52.
[2] Deveraux, Q.L. et al. (1998) EMBO J 17, 2215-23.
[3] Altieri, D.C. et al. (1999) Lab Invest 79, 1327-33.
[4] Tamm, I. et al. (2000) Clin Cancer Res 6, 1796-803.
[5] Kasof, G.M. and Gomes, B.C. (2001) J Biol Chem 276, 3238-46.
[6] Deveraux, Q.L. et al. (1997) Nature 388, 300-4. |
| | XIAP Antibody Preparation Products And Raw materials |
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