Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]-

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Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- Basic information
Product Name:Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]-
Synonyms:Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]-
CAS:1162665-52-2
MF:C24H37N4O6PS
MW:540.61
EINECS:
Product Categories:
Mol File:1162665-52-2.mol
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- Structure
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- Chemical Properties
Boiling point 681.0±65.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
pka7.50±0.20(Predicted)
Safety Information
MSDS Information
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- Usage And Synthesis
UsesIDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies[1].
References[1] Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor
Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]- Preparation Products And Raw materials
Tag:Methanesulfonamide, N-[(1S)-3-[(5S)-1-(3,3-dimethylbutyl)-5-(1,1-dimethylethyl)-2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl]-1-ethoxy-1,4-dihydro-1-oxido-2,4,1-benzodiazaphosphorin-7-yl]-(1162665-52-2) Related Product Information
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