Docetaxel Hydroxy-tert-butyl-carbamate

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Docetaxel Hydroxy-tert-butyl-carbamate Basic information
Product Name:Docetaxel Hydroxy-tert-butyl-carbamate
Synonyms:Docetaxel Metabolite 2, Hydroxy Taxotere, RPR 104952;Benzenepropanoic acid, α-hydroxy-β-[[(2-hydroxy-1,1-dimethylethoxy)carbonyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl est...;Docetaxel Impurity 63;Benzenepropanoic acid, α-hydroxy-β-[[(2-hydroxy-1,1-dimethylethoxy)carbonyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-;RPR 104952/Docetaxel Hydroxy-tert-butyl-carbamate;Docetaxel Metabolite
CAS:154044-57-2
MF:C43H53NO15
MW:823.88
EINECS:
Product Categories:Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;All Inhibitors
Mol File:154044-57-2.mol
Docetaxel Hydroxy-tert-butyl-carbamate Structure
Docetaxel Hydroxy-tert-butyl-carbamate Chemical Properties
Melting point 165-168°C
Boiling point 932.9±65.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly, Heated), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka10.86±0.46(Predicted)
color White to Off-White
Safety Information
MSDS Information
Docetaxel Hydroxy-tert-butyl-carbamate Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA metabolite of Docetaxel, an antineoplastic. An antimitotic agent that promotes the assembly of microtublules and inhibits their depolymerization to free tubulin
UsesThe main metabolite of Docetaxel (D494420), an antineoplastic.
Docetaxel Hydroxy-tert-butyl-carbamate Preparation Products And Raw materials
Tag:Docetaxel Hydroxy-tert-butyl-carbamate(154044-57-2) Related Product Information
Docetaxel Methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate (2R,3S)-Boc-3-Phenylisoserine Docetaxel Docetaxel Impurity 15 2-Azetidinone, 3-hydroxy-4-phenyl-1-[(1S)-1-phenylethyl]-, (3R,4S)- 4-Dichloroethoxy-carbonyl docetaxel HLCSYHHJEMPKSY-RRKHLBDSSA-N (2S,3S)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate Docetaxel Impurity 36 Docetaxel impurity 1/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Docetaxel Impurity 5 2-Debenzoyl-2-pentenoyl Docetaxel 13-O-(Triethylsilyl) Baccatin III 10-Oxo Docetaxel 7-Epi-docetaxel (Docetaxel Impurity C) Paclitaxel PIYPODQNLLWXJG-VHSXEESVSA-N