|
|
| | N-Desmethyl Tamoxifen Hydrochloride Basic information |
| | N-Desmethyl Tamoxifen Hydrochloride Chemical Properties |
| Melting point | 225-227°C | | storage temp. | room temp | | solubility | DMSO: ≥20mg/mL | | form | solid | | color | White to off-white | | Stability: | Light sensitive | | InChI | 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-; | | InChIKey | GMLHJWZEYLTNJW-BJFQDICYSA-N | | SMILES | Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3 |
| Hazard Codes | T,N | | Risk Statements | 45-46-60-50/53 | | Safety Statements | 53-45-60-61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Carc. 1B Repr. 1B |
| | N-Desmethyl Tamoxifen Hydrochloride Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Uses | A main metabolite of the anti-cancer drug Tamoxifen (T006000). | | Uses | N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes. | | Biochem/physiol Actions | N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor. | | IC 50 | PKC |
| | N-Desmethyl Tamoxifen Hydrochloride Preparation Products And Raw materials |
|