- 4-Chlorovalerophenone
-
- $0.00 / 1KG
-
2026-03-20
- CAS:25017-08-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
- 4-Chlorovalerophenone
-
- $0.00 / 1kg
-
2025-08-20
- CAS:25017-08-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1
- 4-Chlorovalerophenone
-
- $100.00 / 1KG
-
2025-03-21
- CAS:25017-08-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000000
|
| | 4-Chlorovalerophenone Basic information |
| Product Name: | 4-Chlorovalerophenone | | Synonyms: | 4-CHLOROVALEROPHENONE;4'-CHLOROPENTANOPHENONE;1-(4-CHLOROPHENYL)-1-PENTANONE;TIMTEC-BB SBB005774;P-CHLOROVALEROPHENONE;1-(4-chlorophenyl)pentan-1-one;1-Pentanone, 1-(4-chlorophenyl)-;1-(4-Chlorophenyl)pentane-1-one | | CAS: | 25017-08-7 | | MF: | C11H13ClO | | MW: | 196.67 | | EINECS: | 246-566-4 | | Product Categories: | Acetophenone Series | | Mol File: | 25017-08-7.mol |  |
| | 4-Chlorovalerophenone Chemical Properties |
| Melting point | 29-33 °C | | Boiling point | 156 °C / 14mmHg | | density | 1.0753 (rough estimate) | | refractive index | 1.5364 (estimate) | | Fp | 30 °C | | storage temp. | Sealed in dry,Room Temperature | | form | fused solid | | color | Off-white to faint yellow | | InChI | InChI=1S/C11H13ClO/c1-2-3-4-11(13)9-5-7-10(12)8-6-9/h5-8H,2-4H2,1H3 | | InChIKey | XMUGWCSIQUJOFA-UHFFFAOYSA-N | | SMILES | C(C1=CC=C(Cl)C=C1)(=O)CCCC | | CAS DataBase Reference | 25017-08-7(CAS DataBase Reference) |
| | 4-Chlorovalerophenone Usage And Synthesis |
| Chemical Properties | white to yellow crystalline low melting solid | | Uses |
4-Chlorovalerophenone is often used as a pharmaceutical intermediate.
| | Synthesis |
A mixture of 346 ml of chlorobenzene and 120 g of valeryl chloride is treated, at room temperature, in the course of 1 hour with portions of aluminium chloride and the mixture is at the same time heated to 70°. The mixture is stirred for a further hour at this temperature and then cooled to 25° and the dark red reaction mixture is poured on to 1,000 g of ice. Concentrated hydrochloric acid is added and the mixture is then extracted with ethyl acetate. The organic extract is washed with 2 N hydrochloric acid, filtered through a diatomaceous earth formulation (Hyflo) and washed with further 2 N hydrochloric acid, twice with water, with a 2 N aqueous solution of sodium carbonate and with water. It is dried over sodium sulphate and filtered and the filtrate is evaporated under reduced pressure. The residue is distilled; 4-Chlorovalerophenone is obtained at 155°-156°/14 mm Hg; the product crystallises and melts at 28°-30°.
|
| | 4-Chlorovalerophenone Preparation Products And Raw materials |
|