4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-

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4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
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4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Basic information
Product Name:4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-
Synonyms:4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-;Cholesterol 24-hydroxylase-IN-2
CAS:1613481-52-9
MF:C20H23FN4O
MW:354.42
EINECS:
Product Categories:
Mol File:1613481-52-9.mol
4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Structure
4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Chemical Properties
Boiling point 550.6±50.0 °C(Predicted)
density 1.28±0.1 g/cm3(Predicted)
pka3.39±0.27(Predicted)
Safety Information
MSDS Information
4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Usage And Synthesis
UsesCholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC50 of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals[1].
References[1] Koike Tatsuki, et al. Preparation of arylpiperidines and arylpiperazines as radiolabeled compounds for use in imaging of cholesterol 24-hydroxylase. World Intellectual Property Organization, WO2015190613 A1 2015-12-17
4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Preparation Products And Raw materials
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