4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel-

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4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- manufacturers

  • LSD1-IN-13
  • LSD1-IN-13 pictures
  • $2785.00
  • 2026-05-11
  • CAS:2170212-33-4
  • Purity:
  • Supply Ability: 10g
4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Basic information
Product Name:4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel-
Synonyms:4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel-;LSD1-IN-13
CAS:2170212-33-4
MF:C23H29N3O2S
MW:411.56
EINECS:
Product Categories:
Mol File:2170212-33-4.mol
4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Structure
4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Chemical Properties
Boiling point 596.9±60.0 °C(Predicted)
density 1.30±0.1 g/cm3(Predicted)
pka10.55±0.10(Predicted)
Safety Information
MSDS Information
4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Usage And Synthesis
UsesLSD1-IN-13 (compound 7e) is an orally active and potent LSD1 inhibitor, with an IC50 of 24.43 nM. LSD1-IN-13 can activate CD86 expression, with an EC50 of 470 nM. LSD1-IN-13 induces differentiation of AML (acute myeloid leukemia) cell lines[1].
in vivo

LSD1-IN-13 (compound 7e) (MV-4-11 xenograft mice, 0-20 mg/kg, Orally, daily for 15 days) suppresses tumor growth significantly in a dose-dependent manner[1].

References[1] Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349. DOI:10.1021/acs.jmedchem.1c02156
4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel- Preparation Products And Raw materials
Tag:4-Piperidinemethanamine, N-[(1R,2S)-2-[2,3-dihydro-1-(phenylsulfonyl)-1H-indol-5-yl]cyclopropyl]-, rel-(2170212-33-4) Related Product Information
1H-Indole-5-carboxamide, 2,3-dihydro-N-[(4-methylphenyl)methyl]-1-[(4-methylphenyl)sulfonyl]- 4-(3,4-dihydroquinolin-1(2H)-ylsulfonyl)aniline(SALTDATA: FREE) 1-[(4-bromophenyl)sulfonyl]-1,2,3,4-tetrahydroquinoline N-(4-(INDOLINYLSULFONYL)PHENYL)ETHANAMIDE 1H-Indole, 5-bromo-2,3-dihydro-3-methyl-1-(phenylsulfonyl)- 1-(Phenylsulfonyl)indolin-6-amine