| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:(S)-3-(5-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
CAS:2829898-76-0
Purity:95%HPLC Package:250MG;1G Remarks:212048
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| Company Name: |
shandong XuanHong Pharmaceutical Technology Co.,Ltd
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| Tel: |
+86-0531-88801869 15090917080 |
| Email: |
sciencechem@163.com |
| Products Intro: |
Product Name:2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)-
CAS:2829898-76-0
Purity:98% Package:100g;1000g
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| | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)- Basic information |
| Product Name: | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)- | | Synonyms: | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)-;(3S)-3-(5-bromo-1-oxo-isoindolin-2-yl)piperidine-2,6-dione;(3S)-3-(5-Bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione;(3S)Lenalidomide-5-Br | | CAS: | 2829898-76-0 | | MF: | C13H11BrN2O3 | | MW: | 323.14 | | EINECS: | | | Product Categories: | | | Mol File: | 2829898-76-0.mol |  |
| | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)- Chemical Properties |
| Boiling point | 587.6±50.0 °C(Predicted) | | density | 1.688±0.06 g/cm3(Predicted) | | pka | 10.60±0.40(Predicted) | | InChI | InChI=1S/C13H11BrN2O3/c14-8-1-2-9-7(5-8)6-16(13(9)19)10-3-4-11(17)15-12(10)18/h1-2,5,10H,3-4,6H2,(H,15,17,18)/t10-/m0/s1 | | InChIKey | CMRQAKJTXKOGSF-JTQLQIEISA-N | | SMILES | N1C(=O)CC[C@H](N2CC3=C(C2=O)C=CC(Br)=C3)C1=O |
| | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)- Usage And Synthesis |
| Uses | (3S)Lenalidomide-5-Br is a ligand for E3 ubiquitinase. (3S)Lenalidomide-5-Br can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608)[1]. | | IC 50 | Cereblon | | References | [1] Preparation of imidazopyridine derivatives for treating disorders. World Intellectual Property Organization, WO2024077244 A1. 2024-04-11. |
| | 2,6-Piperidinedione, 3-(5-bromo-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, (3S)- Preparation Products And Raw materials |
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