ChemicalBook > Product Catalog >Natural Products >Terpenes >(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one

(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one

(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Suppliers list
Company Name: Chengdu Greenpure Biopharma CO.,Ltd
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Products Intro: Product Name:Taraxerone
CAS:514-07-8
Purity:98% Package:5mg Remarks:Triterpenoids
Company Name: Chengdu GLP biotechnology Co Ltd
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Products Intro: Product Name:Taraxasterol
CAS:514-07-8
Purity:98% Package:1g;5g;10g
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Products Intro: Product Name:Taraxerone
CAS:514-07-8
Purity:0.98 Package:10mg;20mg;50mg;100mg
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Products Intro: Product Name:(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
CAS:514-07-8
Purity:0.99 Package:5KG;1KG
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Products Intro: Product Name:Taraxerone
CAS:514-07-8
Purity:98.5% Package:20 mg Remarks:Reach out to us for more information about custom solutions.
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Basic information
Product Name:(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
Synonyms:(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one;D-Friedoolean-14-en-3-one;Taraxera-14-ene-3-one;Taraxerone, 98%, from Adenophora tetraphylla(Thunb.)Fisch;Taraxeron;27-Norolean-14-en-3-one,13-methyl-, (13a)-;Tarxerone;27-Norolean-14-en-3-one, 13-methyl-, (13α)-
CAS:514-07-8
MF:C30H48O
MW:424.7
EINECS:
Product Categories:
Mol File:514-07-8.mol
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Structure
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Chemical Properties
Melting point 241-243 °C
Boiling point 488.3±44.0 °C(Predicted)
density 1.01±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
color White to off-white
LogP10.480 (est)
Safety Information
HS Code 29143990
MSDS Information
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Usage And Synthesis
UsesTaraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
DefinitionChEBI: A natural product found in Cupania cinerea.
in vivo

Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].

References[1] Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14. DOI:10.1016/j.fct.2012.04.031
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Preparation Products And Raw materials
Tag:(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one(514-07-8) Related Product Information
Terrestrosin D dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate Madecassic acid taraxasteryl acetate Madecassoside Taraxasterol roburic acid Poricoic acid A(F) Terrestrosin K ALLEOSIDE A Carboxyatractyloside Pachymic acid taraxerol acetate taraxerol

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