| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
- NSC 55655
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- $50.00
-
2026-08-08
- CAS:36140-65-5
- Purity: 99.39%
- Supply Ability: 10g
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| | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Basic information |
| Product Name: | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione | | Synonyms: | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione;NSC 55655;2,4-Thiazolidinedione, 5-[(2-nitrophenyl)methylene]-;5-[Methylidene]thiazolidine-2,4-dione;5-[(2-Nitrophenyl)methylidene]-1，3-thiazolidine-2，4-dione;5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione;5-(2-Nitrobenzylidene)thiazolidine-2,4-dione | | CAS: | 36140-65-5 | | MF: | C10H6N2O4S | | MW: | 250.23 | | EINECS: | | | Product Categories: | | | Mol File: | 36140-65-5.mol | ![5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Structure](CAS/GIF/36140-65-5.gif) |
| | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Chemical Properties |
| Melting point | 140-142 °C(Solvent: Methanol) | | density | 1.595±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 5.678±0.10(predicted) |
| | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Usage And Synthesis |
| Uses | 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione (Compound 4) has antimicrobial, anti-diabetic and antioxidant activities. 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione inhibits B. subtilis, S. aureus, K. pneumonia, E. coli, and S. typhi with MICs of 4.5-9.9 μΜ/mL, and inhibits A. niger and C. albicans with MICs of 4.99 μΜ/mL[1]. | | References | [1] Elkamhawy A, et al. Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents. Eur J Med Chem. 2020 Feb 15;188:111955. DOI:10.1016/j.ejmech.2019.111955 |
| | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Preparation Products And Raw materials |
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